Scientific Papers

In this page scientific papers, related to the development of the CAPICE project, will be announced and made available for download.

2022

M. Leone, R. Kuja-Halkola, A. Leval, A. Butwicka, J. Skov, R. Zhang, S. Liu, H. Larsson, S. E. Bergen,, "Genetic and Environmental Contribution to the Co-Occurrence of Endocrine-Metabolic Disorders and Depression: A Nationwide Swedish Study of Siblings", Published Online, 21 Septemper 2022), https://doi.org/10.1176/appi.ajp.21090954

M. Jović, K. Agarwal, A. Whitehouse, S.M. van den Berg, "Harmonized Phenotypes for Anxiety, Depression, and Attention-Deficit Hyperactivity Disorder (ADHD)", J Psychopathol Behav Assess (February 2022). https://doi.org/10.1007/s10862-021-09925-9

M. Leone, R. Kuja-Halkola, A. Leval, B. M. D'Onofrio, H. Larsson, P. Lichtenstein, S. E. Bergen, "Association of severe childhood infections with depression and intentional self-harm in adolescents and young adults, Brain, Behavior, and Immunity", Volume 99, 2022, Pages 247-255, ISSN 0889-1591, https://doi.org/10.1016/j.bbi.2021.10.004.

E. Haan, K.E. Westmoreland, L. Schellhas, H.M. Sallis, G. Taylor, L. Zuccolo, M.R. Munafò, "Prenatal smoking, alcohol and caffeine exposure and offspring externalising disorders: A systematic review and meta-analysis", Preprint, medRxiv, https://doi.org/10.1101/2021.06.02.21258212

2021

E. Haan, H.M Sallis, L. Zuccolo, J. Labrecque, E. Ystrom, T. Reichborn-Kjennerud, O.A. Andreassen, A. Havdahl, M.R. Munafò, "Prenatal smoking, alcohol and caffeine exposure and maternal reported adhd symptoms in childhood: triangulation of evidence using negative control and polygenic risk score analyses", Addiction (Abingdon, England), November 2021 Nov 17. https://doi.org/10.1111/add.15746.

E. Haan, H.M Sallis, E. Ystrom, P.R. Njølstad, O.A. Andreassen, T. Reichborn-Kjennerud, M.R. Munafò, A. Havdahl, L. Zuccolo, "Maternal and offspring genetic risk score analyses of fetal alcohol exposure and attention-deficit hyperactivity disorder risk in offspring", Alcoholism, 45(10), 2090–2102, September 2021.

A.E. Tate, S. Liu, R. Zhang, Z. Yilmaz, J.T. Larsen, L.V. Petersen, C.M. Bulik, A.M. Svensson, S. Gudbjörnsdottir, H. Larsson, A. Butwicka, R. Kuja-Halkola, "Association and Familial Coaggregation of Type 1 Diabetes and Eating Disorders: A Register-Based Cohort Study in Denmark and Sweden", Diabetes Care, 44(5):1143-1150, May 2021.

S. Doering , P. Lichtenstein, C. Gillberg, R. Kuja-Halkola, S. Lundström, "Internalizing and neurodevelopmental problems in young people: Educational outcomes in a large population-based cohort of twins", Psychiatry Research, April 2021 298:113794. doi:10.1016/j.psychres.2021.113794.

L. Schellhas, E. Haan, K.E. Easey, R.E. Wootton, H.M Sallis, G.C. Sharp, M.R. Munafò, L. Zuccolo, "Maternal and child genetic liability for smoking and caffeine consumption and child mental health: An intergenerational genetic risk score analysis in the ALSPAC cohort", Addiction, April 2021 https://doi.org/10.1111/add.15521.

K. E. Easey, R. E. Wootton, H. M. Sallis, E. Haan, L. Schellhas, M. R. Munafò, N. J. Timpson, L. Zuccolo, "Characterization of alcohol polygenic risk scores in the context of mental health outcomes: Within-individual and intergenerational analyses in the Avon Longitudinal Study of Parents and Children, Drug and Alcohol Dependence", Volume 221, April 2021, 108654, ISSN 0376-8716, https://doi.org/10.1016/j.drugalcdep.2021.108654.

E.S. Jami, A.R. Hammerschlag, M. Bartels, C.M. Middeldorp, "Parental characteristics and offspring mental health and related outcomes: a systematic review of genetically informative literature", Translational Psychiatry, 11, 197 (2021), April 2021.

H. Ask, R. Cheesman, E.S. Jami, D. Levey, K. Purves, H. Weber, "Genetic contributions to anxiety disorders: Where we are and where we are heading", Psychological Medicine, 1-16, February 2021.

H.S.R. Rajula, M. Manchia, K. Agarwal, W.A. Akingbuwa, A.G. Allegrini, E. Diemer, S. Doering, E. Haan, E.S. Jami, V. Karhunen, M. Leone, L. Schellhas, A. Thompson, S.M. van den Berg, S.E. Bergen, R. Kuja-Halkola, A.R. Hammerschlag, M.R. Järvelin, A. Leval, P. Lichtenstein, S. Lundstrom, M. Mauri, M.R. Munafò, D. Myers, R. Plomin, K. Rimfeld, H. Tiemeier, E. Ystrom, V. Fanos, M. Bartels, C.M. Middeldorp, "Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network", European Child & Adolescent Psychiatry, Springer, January 2021.

2020

M. Leone, R. Kuja-Halkola, A. Leval, B.M. D’Onofrio, H. Larsson, P. Lichtenstein, S.E. Bergen, "Association of Youth Depression With Subsequent Somatic Diseases and Premature Death ", JAMA Psychiatry, December 2020.

A.G. Allegrini, V. Karhunen, J.R.I. Coleman, S. Selzam, K. Rimfeld, S. von Stumm, J.B. Pingault, R. Plomin, "Multivariable G-E interplay in the prediction of educational achievement", PLoS Genetics 16(11):e1009153, November 2020.

H.S.R. Rajula, M. Manchia, B. Carpiniello, V. Fanos, "Big data in severe mental illness: the role of electronic monitoring tools and metabolomics", Personalized Medicine, Future Medicine, October 2020.

H.S.R. Rajula, G. Verlato, M. Manchia, N. Antonucci, V. Fanos, "Comparison of Conventional Statistical Methods with Machine Learning in Medicine: Diagnosis, Drug Development, and Treatment", Medicina 56(9), (2020) 455, MDPI, September 2020.

C. Murphy, T. Brown, H. Trickey, J. Sanders, R. Blaylock, C. Dean C., M. Hennsessy, L. Schellhas, G.C. Sharp, L. Zuccolo, M.R. Munafò, K. Cairns, M. Booker, P. Tennant, J. Fisher, E. Lee, E. Williams, E. Duff, I. Petersen, A. Marshall, "It remains unclear whether caffeine causes adverse pregnancy outcomes; but naive policy recommendations could cause harm [Letter to the editor]", BMJ Evidence-Based Medicine, September 2020

W.A. Akingbuwa, A.R. Hammerschlag, E.S. Jami, et al, "Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42 998 Individuals: A Meta-Analysis ", JAMA Psychiatry, April 2020.

2019

S. Doering , P. Lichtenstein, C. Gillberg, C.M. Middeldorp, M. Bartels, R. Kuja-Halkola, S. Lundström, "Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies". BMC Psychiatry. 2019 Nov 14;19(1):363. doi:10.1186/s12888-019-2349-3.

M. Manchia, V. Fanos, "Childhood and adolescence psycopathology? The ACTION and CAPICE Projects", "Selected Lectures of the 40th Congress UMEMPS / 15th International Workshop on Neonatology. LECT 72", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 8, no. 2, page. 48-49, October 2019.

H.S.R. Rajula, V. Odintsova, M. Manchia, V. Fanos, "Overview of Federated facility to Harmonize and Analyze data in cohorts", "Selected Abstracts of the 40th Congress UMEMPS / 15th International Workshop on Neonatology. ABS 33", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 8, no. 2, page. 25-26, October 2019.

H.S.R. Rajula, M. Manchia, K. Agarwal, W.A. Akingbuwa, A.G. Allegrini, E. Diemer, S. Doering, E. Haan, E.S. Jami, V. Karhunen, M. Leone, L. Schellhas, A. Thompson, M. Mauri, V. Fanos, M. Bartels, C.M. Middeldorp, "Overview of CAPICE – Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe - an EU Marie Skłodowska-Curie International Training Network", "Selected Abstracts of the 40th Congress UMEMPS / 15th International Workshop on Neonatology. ABS 55", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 8, no. 2, page. 41-42, October 2019.

H.S.R. Rajula, V. Odintsova, M. Manchia, V. Fanos, "Overview of Federated Facility to Harmonize, Analyze and Management of Missing Data in Cohorts", Applied Sciences, MDPI, October 2019, 9, 4103.

A.G. Allegrini, R. Cheesman, K. Rimfeld, S. Selzam, J.B. Pingault, T.C. Eley, R. Plomin, "The p factor: genetic analyses support a general dimension of psychopathology in childhood and adolescence", Journal of Child Psychology and Psychiatry 61(1), September 2019.

P. Wiklund, V. Karhunen, R. C. Richmond, P. Parmar, A. Rodriguez, M. De Silva, M. Wielscher, F. I. Rezwan, T. G. Richardson, J. Veijola, K.H. Herzig, J. W. Holloway, C. L. Relton, S. Sebert, M.R. Järvelin, "DNA methylation links prenatal smoking exposure to later life health outcomes in offspring", Clinical Epigenetics, Springer, July 2019.

A.G. Allegrini, S. Selzam, K. Rimfeld, S. von Stumm, J. B. Pingault, R. Plomin, "Genomic prediction of cognitive traits in childhood and adolescence", Molecular Psychiatry, p. 1, Apr. 2019.

C.G. Sharp, L. Schellhas, S.S. Richardson, D.A. Lawlor, "Time to cut the cord: Recognizing and addressing the imbalance of DOHaD research towards the study of maternal pregnancy exposures", Journal of Developmental Origins of Health and Disease, March 2019, 10(5), 509–512. https://doi.org/10.1017/S2040174419000072

2018

M. Manchia, V. Fanos, "Unraveling the complex genetics of childhood and adolescent psychopathology, including aggression, through international collaborations: an update on the CAPICE and ACTION projects", "Selected Lectures of the 14th International Workshop on Neonatology. LECT 31", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 7, no. 2, pages 38-39, 2018

H.S.R. Rajula, M. Manchia, V. Fanos, "The role of big data in neuropsychiatric disorders: a focus on metabolomics", "Selected Lectures of the 14th International Workshop on Neonatology. LECT 32", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 7, no. 2, pages 39-41, 2018

H.S.R Rajula, A.G. Allegrini, E. Shahid, K. Agarwal, V. Karhunen, O. Akingbuwa, E. Haan, E. Diemer, L. Schellhas, A. Thompson, S. Doering, M. Leone, V. Fanos, "CAPICE – Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe.", "Selected Abstracts of the 14th International Workshop on Neonatology. ABS 47", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 7, no. 2, pages 42-46, 2018

H.S.R. Rajula, M. Mauri, "Journey of first year of my Ph.D. at University of Cagliari", "Selected Abstracts of the 14th International Workshop on Neonatology. ABS 49", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 7, no. 2, pages 46-47, 2018

M. Mauri, V. Fanos, "Sharing research: communication can help", "Selected Lectures of the 14th International Workshop on Neonatology. LECT 33", Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), vol. 7, no. 2, pages 41-43, 2018

H.S.R. Rajula, M. Mauri, V. Fanos, "Scale-free networks in metabolomics", Bioinformation Volume 14 (3): 140-144, 2018 - bioinformation.net

C.M. Middeldorp, N.R. Wray, "The value of polygenic analyses in psychiatry", World Psychiatry, Volume 17, Issue 1, February 2018, Pages 26–28, PubMed id: 29352547

2017